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Emerging role of mRNA epitranscriptomic regulation in chemoresistant cancer cells

Cancer persister cells remain a significant barrier to effective anti-cancer therapy. We found that melanoma persister cells undergo a reversible reprogramming of mRNA translation. A subset of mRNAs, harboring N6-methyladenosine in their 5ʹ-untranslated regions, is translationally up-regulated in an...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Shen, Shensi, Sun, Xiaoxiao
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199735/
https://ncbi.nlm.nih.gov/pubmed/32391421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1728467
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