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Priming of Antiviral CD8 T Cells without Effector Function by a Persistently Replicating Hepatitis C-Like Virus

Immune-competent animal models for the hepatitis C virus (HCV) are nonexistent, impeding studies of host-virus interactions and vaccine development. Experimental infection of laboratory rats with a rodent hepacivirus isolated from Rattus norvegicus (RHV) is a promising surrogate model due to its rec...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Hartlage, Alex S., Walker, Christopher M., Kapoor, Amit
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199419/
https://ncbi.nlm.nih.gov/pubmed/32102885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00035-20
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