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Pseudorabies Virus Infection of Epithelial Cells Leads to Persistent but Aberrant Activation of the NF-κB Pathway, Inhibiting Hallmark NF-κB-Induced Proinflammatory Gene Expression

The nuclear factor kappa B (NF-κB) is a potent transcription factor, activation of which typically results in robust proinflammatory signaling and triggering of fast negative feedback modulators to avoid excessive inflammatory responses. Here, we report that infection of epithelial cells, including...

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Vydáno v:J Virol
Hlavní autoři: Romero, Nicolás, Van Waesberghe, Cliff, Favoreel, Herman W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199412/
https://ncbi.nlm.nih.gov/pubmed/32132236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00196-20
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