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Internalization of Pseudorabies Virus Glycoprotein B Is Mediated by an Interaction between the YQRL Motif in Its Cytoplasmic Domain and the Clathrin-Associated AP-2 Adaptor Complex

The cytoplasmic domain of pseudorabies virus (PRV) glycoprotein B (gB) contains three putative internalization motifs. Previously, we demonstrated that the tyrosine-based YQRL motif at positions 902 to 905, but not the YMSI motif at positions 864 to 867 or the LL doublet at positions 887 and 888, is...

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Autors principals: Van Minnebruggen, Geert, Favoreel, Herman W., Nauwynck, Hans J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC479101/
https://ncbi.nlm.nih.gov/pubmed/15280493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8852-8859.2004
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