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Internalization of Pseudorabies Virus Glycoprotein B Is Mediated by an Interaction between the YQRL Motif in Its Cytoplasmic Domain and the Clathrin-Associated AP-2 Adaptor Complex

The cytoplasmic domain of pseudorabies virus (PRV) glycoprotein B (gB) contains three putative internalization motifs. Previously, we demonstrated that the tyrosine-based YQRL motif at positions 902 to 905, but not the YMSI motif at positions 864 to 867 or the LL doublet at positions 887 and 888, is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Van Minnebruggen, Geert, Favoreel, Herman W., Nauwynck, Hans J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15280493/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.16.8852-8859.2004
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