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HIV-1-Specific Chimeric Antigen Receptor T Cells Fail To Recognize and Eliminate the Follicular Dendritic Cell HIV Reservoir In Vitro

The major obstacle to a cure for HIV infection is the persistence of replication-competent viral reservoirs during antiretroviral therapy. HIV-specific chimeric antigen receptor (CAR) T cells have been developed to target latently infected CD4(+) T cells that express virus either spontaneously or af...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ollerton, Matthew T., Berger, Edward A., Connick, Elizabeth, Burton, Gregory F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199392/
https://ncbi.nlm.nih.gov/pubmed/32161179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00190-20
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