HIV-1 Reservoir Dynamics after Vaccination and Antiretroviral Therapy Interruption Are Associated with Dendritic Cell Vaccine-Induced T Cell Responses

HIV-1-specific immune responses induced by a dendritic cell (DC)-based therapeutic vaccine might have some effect on the viral reservoir. Patients on combination antiretroviral therapy (cART) were randomized to receive DCs pulsed with autologous HIV-1 (n = 24) (DC-HIV-1) or nonpulsed DCs (n = 12) (D...

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Veröffentlicht in:J Virol
Hauptverfasser: Andrés, Cristina, Plana, Montserrat, Guardo, Alberto C., Alvarez-Fernández, Carmen, Climent, Nuria, Gallart, Teresa, León, Agathe, Clotet, Bonaventura, Autran, Brigitte, Chomont, Nicolas, Gatell, Josep M., Sánchez-Palomino, Sonsoles, García, Felipe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542373/
https://ncbi.nlm.nih.gov/pubmed/26109727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01062-15
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