The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females

BACKGROUND: Primary glomerulonephritis (GN) is the leading cause of chronic kidney disease (CKD) and frequently progresses into end stage renal diseases (ESRDs). Shorter leukocyte telomere length (LTL) has been implicated in the CKD susceptibility and diminished kidney function, however, it is uncle...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Sun, Qing, Liu, Junli, Cheng, Guanghui, Dai, Mingkai, Liu, Jiaxi, Qi, Zhenqiang, Zhao, Jingjie, Li, Wei, Kong, Feng, Liu, Gang, Björkholm, Magnus, Xu, Dawei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199377/
https://ncbi.nlm.nih.gov/pubmed/32366311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02347-3
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