Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

Although intramuscular (i.m.) administration is the most commonly used route for licensed vaccines, subcutaneous (s.c.) delivery is being explored for several new vaccines under development. Here, we use rhesus macaques, physiologically relevant to humans, to identify the anatomical compartments and...

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Опубликовано в: :Cell Rep
Главные авторы: Ols, Sebastian, Yang, Lifei, Thompson, Elizabeth A., Pushparaj, Pradeepa, Tran, Karen, Liang, Frank, Lin, Ang, Eriksson, Bengt, Karlsson Hedestam, Gunilla B., Wyatt, Richard T., Loré, Karin
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198771/
https://ncbi.nlm.nih.gov/pubmed/32209459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.111
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