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Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

Although intramuscular (i.m.) administration is the most commonly used route for licensed vaccines, subcutaneous (s.c.) delivery is being explored for several new vaccines under development. Here, we use rhesus macaques, physiologically relevant to humans, to identify the anatomical compartments and...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ols, Sebastian, Yang, Lifei, Thompson, Elizabeth A., Pushparaj, Pradeepa, Tran, Karen, Liang, Frank, Lin, Ang, Eriksson, Bengt, Karlsson Hedestam, Gunilla B., Wyatt, Richard T., Loré, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198771/
https://ncbi.nlm.nih.gov/pubmed/32209459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.111
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