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DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype

People with ataxia-telangiectasia (A-T) display phenotypic variability with regard to progression of immunodeficiency, sino-pulmonary disease, and neurologic decline. To determine the association between differential gene expression, epigenetic state, and phenotypic variation among people with A-T,...

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Pubblicato in:Sci Rep
Autori principali: McGrath-Morrow, Sharon A., Ndeh, Roland, Helmin, Kathryn A., Khuder, Basil, Rothblum-Oviatt, Cynthia, Collaco, Joseph M., Wright, Jennifer, Reyfman, Paul A., Lederman, Howard M., Singer, Benjamin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198504/
https://ncbi.nlm.nih.gov/pubmed/32366930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64514-2
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