Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia

INTRODUCTION: Classic ataxia telangiectasia (A-T) is an autosomal recessive disease characterized by early onset ataxia, immune deficiency, sino-pulmonary disease, lymphoid/solid malignancies and telangiectasias. Prior studies have suggested that chronic inflammation and premature aging may contribu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: McGrath-Morrow, Sharon A., Ndeh, Roland, Collaco, Joseph M., Rothblum-Oviatt, Cynthia, Wright, Jennifer, O’Reilly, Michael A., Singer, Benjamin D., Lederman, Howard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306200/
https://ncbi.nlm.nih.gov/pubmed/30586396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209496
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