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An Engineered Three-Dimensional Stem Cell Niche in the Inner Ear by Applying a Nanofibrillar Cellulose Hydrogel with a Sustained-Release Neurotrophic Factor Delivery System
Although the application of human embryonic stem cells (hESCs) in stem cell–replacement therapy remains promising, its potential is hindered by a low cell survival rate in post-transplantation within the inner ear. Here, we aim to enhance the in vitro and in vivo survival rate and neuronal different...
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| Publicat a: | Acta Biomater |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7198367/ https://ncbi.nlm.nih.gov/pubmed/32156626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.03.007 |
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