The combined risk effect among BIN1, CLU, and APOE genes in Alzheimer’s disease

Genome-wide associations studies (GWAS) are detecting new variants associated with late-onset of Alzheimer’s disease (LOAD), a multifactorial neurodegenerative disorder. The variants rs744373 BIN1, rs11136000 CLU and rs3764650 ABCA7 uncovered by GWAS led to different AD pathways, such as metabolism,...

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Bibliografiske detaljer
Udgivet i:Genet Mol Biol
Main Authors: dos Santos, Lígia Ramos, Almeida, Jucimara Ferreira Figueiredo, Pimassoni, Lúcia Helena Sagrillo, Morelato, Renato Lírio, de Paula, Flavia
Format: Artigo
Sprog:Inglês
Udgivet: Sociedade Brasileira de Genética 2020
Fag:
Human and Medical Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198034/
https://ncbi.nlm.nih.gov/pubmed/31469155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2018-0320
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