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Combined Effects of Alzheimer Risk Variants in the CLU and ApoE Genes on Ventricular Expansion Patterns in the Elderly

The C allele at the rs11136000 locus in the clusterin (CLU) gene is the third strongest known genetic risk factor for late-onset Alzheimer's disease (LOAD). A recent genome-wide association study of LOAD found the strongest evidence of association with CLU at rs1532278, in high linkage disequil...

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Detalles Bibliográficos
Main Authors: Roussotte, Florence F., Gutman, Boris A., Madsen, Sarah K., Colby, John B., Thompson, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012312/
https://ncbi.nlm.nih.gov/pubmed/24806679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5236-13.2014
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