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Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis

Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling cooperates with Tbx transcription factors to promote dorsal mesoderm formation, but their role in myogenesis has been unclear. Using zebrafish, we show that dorsally derived...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Osborn, Daniel P. S., Li, Kuoyu, Cutty, Stephen J., Nelson, Andrew C., Wardle, Fiona C., Hinits, Yaniv, Hughes, Simon M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197714/
https://ncbi.nlm.nih.gov/pubmed/32345657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.184689
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