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Cdkn1c drives muscle differentiation through a positive feedback loop with Myod
Differentiation often requires conversion of analogue signals to a stable binary output through positive feedback. Hedgehog (Hh) signalling promotes myogenesis in the vertebrate somite, in part by raising the activity of muscle regulatory factors (MRFs) of the Myod family above a threshold. Hh is kn...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044464/ https://ncbi.nlm.nih.gov/pubmed/21147088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.010 |
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