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Cdkn1c drives muscle differentiation through a positive feedback loop with Myod

Differentiation often requires conversion of analogue signals to a stable binary output through positive feedback. Hedgehog (Hh) signalling promotes myogenesis in the vertebrate somite, in part by raising the activity of muscle regulatory factors (MRFs) of the Myod family above a threshold. Hh is kn...

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Autors principals: Osborn, Daniel P.S., Li, Kuoyu, Hinits, Yaniv, Hughes, Simon M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044464/
https://ncbi.nlm.nih.gov/pubmed/21147088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.010
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