Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis

Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new drug combinations to trigger defatting in three human culture models, primary hepatocytes with induced steatosis, primary hepatocytes isolat...

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Библиографические подробности
Опубликовано в: :Dis Model Mech
Главные авторы: Aoudjehane, Lynda, Gautheron, Jérémie, Le Goff, Wilfried, Goumard, Claire, Gilaizeau, Julia, Nget, Chan Sonavine, Savier, Eric, Atif, Muhammad, Lesnik, Philippe, Morichon, Romain, Chrétien, Yves, Calmus, Yvon, Scatton, Olivier, Housset, Chantal, Conti, Filomena
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197711/
https://ncbi.nlm.nih.gov/pubmed/32094147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042663
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