Langerhans Cells From Mice at Birth Express Endocytic- and Pattern Recognition-Receptors, Migrate to Draining Lymph Nodes Ferrying Antigen and Activate Neonatal T Cells in vivo

Antigen capturing at the periphery is one of the earliest, crucial functions of antigen-presenting cells (APCs) to initiate immune responses. Langerhans cells (LCs), the epidermal APCs migrate to draining lymph nodes (DLNs) upon acquiring antigens. An arsenal of endocytic molecules is available to t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Becerril-García, Miguel Angel, Yam-Puc, Juan Carlos, Maqueda-Alfaro, Raúl, Beristain-Covarrubias, Nonantzin, Heras-Chavarría, Monica, Gallegos-Hernández, Isis Amara, Calderón-Amador, Juana, Munguía-Fuentes, Rosario, Donis-Maturano, Luis, Flores-Langarica, Adriana, Flores-Romo, Leopoldo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197463/
https://ncbi.nlm.nih.gov/pubmed/32395120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00744
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