The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs

Covalent chemical modifications of cellular RNAs directly impact all biological processes. However, our mechanistic understanding of the enzymes catalyzing these modifications, their substrates and biological functions, remains vague. Amongst RNA modifications N(6)-methyladenosine (m(6)A) is widespr...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Ignatova, Valentina V., Stolz, Paul, Kaiser, Steffen, Gustafsson, Tobias H., Lastres, Palma Rico, Sanz-Moreno, Adrián, Cho, Yi-Li, Amarie, Oana V., Aguilar-Pimentel, Antonio, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Becker, Lore, Marschall, Susan, Kraiger, Markus, Garrett, Lillian, Seisenberger, Claudia, Hölter, Sabine M., Borland, Kayla, Van De Logt, Erik, Jansen, Pascal W.T.C., Baltissen, Marijke P., Valenta, Magdalena, Vermeulen, Michiel, Wurst, Wolfgang, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, Rando, Oliver J., Kellner, Stefanie M., Bultmann, Sebastian, Schneider, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197354/
https://ncbi.nlm.nih.gov/pubmed/32217665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333369.119
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