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Positive autofeedback regulation of Ptf1a transcription generates the levels of PTF1A required to generate itch circuit neurons
Peripheral somatosensory input is modulated in the dorsal spinal cord by a network of excitatory and inhibitory interneurons. PTF1A is a transcription factor essential in dorsal neural tube progenitors for specification of these inhibitory neurons. Thus, mechanisms regulating Ptf1a expression are ke...
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| Izdano u: | Genes Dev |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7197352/ https://ncbi.nlm.nih.gov/pubmed/32241803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.332577.119 |
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