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DNA methylation links intrauterine stress with abnormal nephrogenesis

Scientists have long wondered how maternal diabetes, malnutrition and placental dysfunction impair fetal nephrogenesis. Anew study discovered a link between prenatal metabolic stress and nephron deficit via dysregulation of DNA methylation — an epigenetic mechanism that is essential for the renewal...

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Publicado en:Nat Rev Nephrol
Autor principal: El-Dahr, Samir S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197214/
https://ncbi.nlm.nih.gov/pubmed/30670870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41581-019-0114-y
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