LRRK2 and GBA Variants Exert Distinct Influences on Parkinson’s Disease-Specific Metabolic Networks

The natural history of idiopathic Parkinson’s disease (PD) varies considerably across patients. While PD is generally sporadic, there are known genetic influences: the two most common, mutations in the LRRK2 or GBA1 gene, are associated with slower and more aggressive progression, respectively. Here...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Schindlbeck, Katharina A, Vo, An, Nguyen, Nha, Tang, Chris C, Niethammer, Martin, Dhawan, Vijay, Brandt, Vicky, Saunders-Pullman, Rachel, Bressman, Susan B, Eidelberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197067/
https://ncbi.nlm.nih.gov/pubmed/31813991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhz280
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