It takes two (Las1 HEPN endoribonuclease domains) to cut RNA correctly

The ribosome biogenesis factor Las1 is an essential endoribonuclease that is well-conserved across eukaryotes and a newly established member of the higher eukaryotes and prokaryotes nucleotide-binding (HEPN) domain-containing nuclease family. HEPN nucleases participate in diverse RNA cleavage pathwa...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Pillon, Monica C., Goslen, Kevin H., Gordon, Jacob, Wells, Melissa L., Williams, Jason G., Stanley, Robin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Enzymology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196650/
https://ncbi.nlm.nih.gov/pubmed/32220933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011193
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