DHHC7-mediated palmitoylation of the accessory protein barttin critically regulates the functions of ClC-K chloride channels

Barttin is the accessory subunit of the human ClC-K chloride channels, which are expressed in both the kidney and inner ear. Barttin promotes trafficking of the complex it forms with ClC-K to the plasma membrane and is involved in activating this channel. Barttin undergoes post-translational palmito...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gorinski, Nataliya, Wojciechowski, Daniel, Guseva, Daria, Abdel Galil, Dalia, Mueller, Franziska E., Wirth, Alexander, Thiemann, Stefan, Zeug, Andre, Schmidt, Silke, Zareba-Kozioł, Monika, Wlodarczyk, Jakub, Skryabin, Boris V., Glage, Silke, Fischer, Martin, Al-Samir, Samer, Kerkenberg, Nicole, Hohoff, Christa, Zhang, Weiqi, Endeward, Volker, Ponimaskin, Evgeni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196637/
https://ncbi.nlm.nih.gov/pubmed/32184353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011049
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