COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10

Coenzyme Q (Q(n)) is a vital lipid component of the electron transport chain that functions in cellular energy metabolism and as a membrane antioxidant. In the yeast Saccharomyces cerevisiae, coq1–coq9 deletion mutants are respiratory-incompetent, sensitive to lipid peroxidation stress, and unable t...

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Vydáno v:J Biol Chem
Hlavní autoři: Bradley, Michelle C., Yang, Krista, Fernández-del-Río, Lucía, Ngo, Jennifer, Ayer, Anita, Tsui, Hui S., Novales, Noelle Alexa, Stocker, Roland, Shirihai, Orian S., Barros, Mario H., Clarke, Catherine F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196636/
https://ncbi.nlm.nih.gov/pubmed/32205446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012420
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