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Preclinical Studies of the Off-Target Reactivity of AFP(158)-Specific TCR Engineered T Cells
Autologous T cells engineered with T receptor genes (TCR) are being studied to treat cancers. We have recently identified a panel of mouse TCRs specific for the HLA-A0201/alpha fetoprotein epitope (AFP(158)) complex and have shown that human T cells engineered with these TCR genes (TCR-Ts) can eradi...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7196607/ https://ncbi.nlm.nih.gov/pubmed/32395117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00607 |
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