Human Hepatocyte Nuclear Factor 4-α Encodes Isoforms with Distinct Transcriptional Functions

HNF4α is a nuclear receptor produced as 12 isoforms from two promoters by alternative splicing. To characterize the transcriptional capacities of all 12 HNF4α isoforms, stable lines expressing each isoform were generated. The entire transcriptome associated with each isoform was analyzed as well as...

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Vydáno v:Mol Cell Proteomics
Hlavní autoři: Lambert, Élie, Babeu, Jean-Philippe, Simoneau, Joël, Raisch, Jennifer, Lavergne, Laurie, Lévesque, Dominique, Jolibois, Émilie, Avino, Mariano, Scott, Michelle S., Boudreau, François, Boisvert, Francois-Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196586/
https://ncbi.nlm.nih.gov/pubmed/32123031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001909
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