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A244 ROLE OF THE NUCLEAR RECEPTOR HNF4α AND ITS MANY ISOFORMS IN COLORECTAL CANCER

BACKGROUND: Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor regulating the expression of intestinal epithelial genes. Up to 12 HNF4α isoforms can be produced by the use of promoters P1 and P2, and alternative splicing. HNF4α has recently been associated with colorectal cancer, an...

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Pubblicato in:J Can Assoc Gastroenterol
Autori principali: Lambert, E, Babeu, J, Levesque, D, Boisvert, F, Boudreau, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508266/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.244
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