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A244 ROLE OF THE NUCLEAR RECEPTOR HNF4α AND ITS MANY ISOFORMS IN COLORECTAL CANCER

BACKGROUND: Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor regulating the expression of intestinal epithelial genes. Up to 12 HNF4α isoforms can be produced by the use of promoters P1 and P2, and alternative splicing. HNF4α has recently been associated with colorectal cancer, an...

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Vydáno v:J Can Assoc Gastroenterol
Hlavní autoři: Lambert, E, Babeu, J, Levesque, D, Boisvert, F, Boudreau, F
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508266/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.244
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