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Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy
Poly-ADP-ribosylation (PARylation) is a fully reversible post-translational modification with key roles in cellular physiology. Due to the multi-domain structure of poly(ADP-ribose) polymerase-1 (PARP1) and the highly dynamic nature of the PARylation reaction, studies on the biochemical mechanism an...
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| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7195430/ https://ncbi.nlm.nih.gov/pubmed/32358582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15858-w |
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