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Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation
Aging is a multifactorial process that depends on diverse molecular and cellular mechanisms, such as genome maintenance and inflammation. The nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP1), which catalyzes the synthesis of the biopolymer poly(ADP-ribose), exhibits an essential role in both pro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459245/ https://ncbi.nlm.nih.gov/pubmed/23050038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/321653 |
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