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Midkine activation of CD8(+) T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth

Brain tumors (gliomas) are heterogeneous cellular ecosystems, where non-neoplastic monocytic cells have emerged as key regulators of tumor maintenance and progression. However, relative to macrophages/microglia, comparatively less is known about the roles of neurons and T cells in glioma pathobiolog...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Guo, Xiaofan, Pan, Yuan, Xiong, Min, Sanapala, Shilpa, Anastasaki, Corina, Cobb, Olivia, Dahiya, Sonika, Gutmann, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195398/
https://ncbi.nlm.nih.gov/pubmed/32358581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15770-3
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