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Midkine activation of CD8(+) T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
Brain tumors (gliomas) are heterogeneous cellular ecosystems, where non-neoplastic monocytic cells have emerged as key regulators of tumor maintenance and progression. However, relative to macrophages/microglia, comparatively less is known about the roles of neurons and T cells in glioma pathobiolog...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7195398/ https://ncbi.nlm.nih.gov/pubmed/32358581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15770-3 |
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