HIF-1α metabolically controls: collagen synthesis and modification in chondrocytes

Endochondral ossification, an important bone formation process in vertebrates, highly depends on proper functioning of growth plate chondrocytes(1). Their proliferation determines longitudinal bone growth and the matrix deposited provides a scaffold for future bone formation. However, these two ener...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Stegen, Steve, Laperre, Kjell, Eelen, Guy, Rinaldi, Gianmarco, Fraisl, Peter, Torrekens, Sophie, Van Looveren, Riet, Loopmans, Shauni, Bultynck, Geert, Vinckier, Stefan, Meersman, Filip, Maxwell, Patrick H., Rai, Jyoti, Weis, MaryAnn, Eyre, David R., Ghesquière, Bart, Fendt, Sarah-Maria, Carmeliet, Peter, Carmeliet, Geert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195049/
https://ncbi.nlm.nih.gov/pubmed/30651640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0874-3
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