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Analyses of lysine aldehyde cross-linking in collagen reveal that the mature cross-link histidinohydroxylysinonorleucine is an artifact

Lysyl oxidase-generated intermolecular cross-links are essential for the tensile strength of collagen fibrils. Two cross-linking pathways can be defined, one based on telopeptide lysine aldehydes and another on telopeptide hydroxylysine aldehydes. Since the 1970s it has been accepted that the mature...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Eyre, David R., Weis, MaryAnn, Rai, Jyoti
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484114/
https://ncbi.nlm.nih.gov/pubmed/30733334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007202
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