Characterization of the Impact of Daclizumab Beta on Circulating Natural Killer Cells by Mass Cytometry

Daclizumab beta is a humanized monoclonal antibody that binds to CD25 and selectively inhibits high-affinity IL-2 receptor signaling. As a former treatment for relapsing forms of multiple sclerosis (RMS), daclizumab beta induces robust expansion of the CD56(bright) subpopulation of NK cells that is...

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Publicado no:Front Immunol
Main Authors: Ranganath, Thanmayi, Simpson, Laura J., Ferreira, Anne-Maud, Seiler, Christof, Vendrame, Elena, Zhao, Nancy, Fontenot, Jason D., Holmes, Susan, Blish, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194113/
https://ncbi.nlm.nih.gov/pubmed/32391016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00714
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