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TIGIT is upregulated by HIV-1 infection and marks a highly functional adaptive and mature subset of natural killer cells

OBJECTIVE: Our objective was to investigate the mechanisms that govern natural killer (NK) cell responses to HIV, with a focus on specific receptor-ligand interactions involved in HIV recognition by NK cells. DESIGN AND METHODS: We first performed a mass cytometry-based screen of NK cell receptor ex...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: VENDRAME, Elena, SEILER, Christof, RANGANATH, Thanmayi, ZHAO, Nancy Q., VERGARA, Rosemary, ALARY, Michel, LABBÉ, Annie-Claude, GUÉDOU, Fernand, POUDRIER, Johanne, HOLMES, Susan, ROGER, Michel, BLISH, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148170/
https://ncbi.nlm.nih.gov/pubmed/32028328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002488
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