Bacteria boost mammalian host NAD metabolism by engaging the deamidated biosynthesis pathway

Nicotinamide adenine dinucleotide (NAD), a cofactor for hundreds of metabolic reactions in all cell types, plays an essential role in metabolism, DNA repair, and aging. However, how NAD metabolism is impacted by the environment remains unclear. Here, we report an unexpected trans-kingdom cooperation...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Shats, Igor, Williams, Jason G., Liu, Juan, Makarov, Mikhail V., Wu, Xiaoyue, Lih, Fred B., Deterding, Leesa J., Lim, Chaemin, Xu, Xiaojiang, Randall, Thomas A., Lee, Ethan, Li, Wenling, Fan, Wei, Li, Jian-Liang, Sokolsky, Marina, Kabanov, Alexander V., Li, Leping, Migaud, Marie E., Locasale, Jason W., Li, Xiaoling
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194078/
https://ncbi.nlm.nih.gov/pubmed/32130883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.02.001
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