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Resolution and quantitation of mercapturic acids derived from crotonaldehyde, methacrolein, and methyl vinyl ketone in the urine of smokers and non-smokers
Using improved HPLC analysis conditions, we report the separation of 3 isomers of mercapturic acid conjugates previously assigned in the literature only to 3-hydroxy-1-methylpropylmercapturic acid (HMPMA-1), a human urinary metabolite of crotonaldehyde. The new conditions, employing a biphenyl colum...
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| Publicado no: | Chem Res Toxicol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7193944/ https://ncbi.nlm.nih.gov/pubmed/31957442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00491 |
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