Heat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells

Luminespib (AUY922), a heat shock proteins 90 inhibitor, has anti-neoplastic and antitumor effects. However, it is not clear whether AUY922 affects events in vascular diseases. We investigated the effects of AUY922 on the platelet-derived growth factor (PDGF)-BB-stimulated proliferation and migratio...

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Veröffentlicht in:Korean J Physiol Pharmacol
Hauptverfasser: Kim, Jisu, Lee, Kang Pa, Kim, Bom Sahn, Lee, Sang Ju, Moon, Byung Seok, Baek, Suji
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Physiological Society and The Korean Society of Pharmacology 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193915/
https://ncbi.nlm.nih.gov/pubmed/32392915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2020.24.3.241
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