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Eomes identifies thymic precursors of self-specific memory-phenotype CD8(+) T cells

Unprimed mice harbor a substantial population of "memory-phenotype" CD8(+) T cells (CD8-MP cells) that exhibit hallmarks of activation and innate-like functional properties. Due to the lack of faithful markers to distinguish CD8-MP cells from bona fide CD8(+) memory T cells, the developmen...

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Publicat a:Nat Immunol
Autors principals: Miller, Christine H., Klawon, David E.J., Zeng, Sharon, Lee, Victoria, Socci, Nicholas D., Savage, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193531/
https://ncbi.nlm.nih.gov/pubmed/32284593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0653-1
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