Elevated T Cell Receptor Signaling Identifies a Thymic Precursor to the TCRαβ(+)CD4(−)CD8β(−) Intraepithelial Lymphocyte Lineage

The origin and developmental pathway of intestinal T cell receptor αβ(+) CD4(−)CD8β(−) intraepithelial lymphocytes (unconventional iIELs), a major population of innate-like resident cytolytic T cells, have remained elusive. By cloning and expressing several TCRs isolated from unconventional iIELs, w...

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Detaylı Bibliyografya
Asıl Yazarlar: McDonald, Benjamin D., Bunker, Jeffrey J., Ishizuka, Isabel E., Jabri, Bana, Bendelac, Albert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188477/
https://ncbi.nlm.nih.gov/pubmed/25131532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.07.008
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