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Potential synergic mechanism of Wutou-Gancao herb-pair by inhibiting efflux transporter P-glycoprotein

Wutou-Gancao herb-pair is extensively used to attenuate the toxicity and enhance the efficacy of aconite. In this study, potential synergic mechanism of the herb pair was investigated by utilizing multiple approaches. In silico and in vitro Caco-2 cell models were applied to study the potential bind...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: He, Yufei, Wei, Zihong, Xie, Ying, Yi, Xiulin, Zeng, Yong, Li, Yazhuo, Liu, Changxiao
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192969/
https://ncbi.nlm.nih.gov/pubmed/32373389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2019.09.004
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