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N,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis

Elucidation of the binding mode of protein–ligand interactions provides insights for the design of new pharmacological tools and drug leads. Specific labeling of target proteins with chemical probes, in which the ligands are conjugated with reacting and detecting groups, can establish the binding po...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Arai, Atsushi, Watanabe, Rei, Hattori, Atsunori, Iio, Keita, Hu, Yaping, Yoneda, Kozo, Kigoshi, Hideo, Kita, Masaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192892/
https://ncbi.nlm.nih.gov/pubmed/32355254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64321-9
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