Impaired Glycoprotein VI-Mediated Signaling and Platelet Functional Responses in CD45 Knockout Mice

BACKGROUND AND OBJECTIVE: CD45 is a receptor protein tyrosine phosphatase present on the surface of all hematopoietic cells except for erythrocytes and platelets. Proteomics studies, however, have demonstrated the presence of a CD45 c-terminal catalytic peptide in platelets. Therefore, we investigat...

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Dettagli Bibliografici
Pubblicato in:Thromb Haemost
Autori principali: Inamdar, Vaishali V., Kostyak, John C., Badolia, Rachit, Dangelmaier, Carol A., Manne, Bhanu Kanth, Patel, Akruti, Kim, Soochong, Kunapuli, Satya P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192241/
https://ncbi.nlm.nih.gov/pubmed/31226719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1692422
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