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Prohibitin 2/PHB2 in Parkin-Mediated Mitophagy: A Potential Therapeutic Target for Non-Small Cell Lung Carcinoma

BACKGROUND: Mitophagy, a selective autophagy process, plays various roles in tumors. Prohibitin 2 (PHB2) is an inner-mitochondrial membrane protein that participates in parkin-induced mitophagy. However, the role of PHB2 in non-small cell lung carcinoma (NSCLC) has not been previously reported. MATE...

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Vydáno v:Med Sci Monit
Hlavní autoři: Zhang, Han, Yin, Chuntong, Liu, Xin, Bai, Xue, Wang, Lei, Xu, Honglin, Ju, Jin, Zhang, Linyou
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191963/
https://ncbi.nlm.nih.gov/pubmed/32320388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.923227
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