Cellular and Molecular Mechanisms of Kidney Injury in 2,8-Dihydroxyadenine Nephropathy

BACKGROUND: Hereditary deficiency of adenine phosphoribosyltransferase causes 2,8-dihydroxyadenine (2,8-DHA) nephropathy, a rare condition characterized by formation of 2,8-DHA crystals within renal tubules. Clinical relevance of rodent models of 2,8-DHA crystal nephropathy induced by excessive aden...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Klinkhammer, Barbara Mara, Djudjaj, Sonja, Kunter, Uta, Palsson, Runolfur, Edvardsson, Vidar Orn, Wiech, Thorsten, Thorsteinsdottir, Margret, Hardarson, Sverrir, Foresto-Neto, Orestes, Mulay, Shrikant R., Moeller, Marcus Johannes, Jahnen-Dechent, Wilhelm, Floege, Jürgen, Anders, Hans-Joachim, Boor, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2020
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191925/
https://ncbi.nlm.nih.gov/pubmed/32086278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019080827
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