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Combination Therapy With Neuraminidase and Polymerase Inhibitors in Nude Mice Infected With Influenza Virus

BACKGROUND: Treatment of immunocompromised, influenza virus–infected patients with the viral neuraminidase inhibitor oseltamivir often leads to the emergence of drug-resistant variants. Combination therapy with compounds that target different steps in the viral life cycle may improve treatment outco...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: Kiso, Maki, Lopes, Tiago J S, Yamayoshi, Seiya, Ito, Mutsumi, Yamashita, Makoto, Nakajima, Noriko, Hasegawa, Hideki, Neumann, Gabriele, Kawaoka, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191623/
https://ncbi.nlm.nih.gov/pubmed/29186472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix606
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