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Enhanced Replication of Highly Pathogenic Influenza A(H7N9) Virus in Humans

To clarify the threat posed by emergence of highly pathogenic influenza A(H7N9) virus infection among humans, we characterized the viral polymerase complex. Polymerase basic 2–482R, polymerase basic 2–588V, and polymerase acidic–497R individually or additively enhanced virus polymerase activity, ind...

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Detalhes bibliográficos
Publicado no:Emerg Infect Dis
Main Authors: Yamayoshi, Seiya, Kiso, Maki, Yasuhara, Atsuhiro, Ito, Mutsumi, Shu, Yuelong, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875272/
https://ncbi.nlm.nih.gov/pubmed/29553313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2404.171509
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