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Staphylococcus aureus SaeR/S-Regulated Factors Decrease Monocyte-Derived Tumor Necrosis Factor–α to Reduce Neutrophil Bactericidal Activity

BACKGROUND: The ability of Staphylococcus aureus to evade killing by human neutrophils significantly contributes to disease progression. In this study, we characterize an influential role for the S. aureus SaeR/S 2-component gene regulatory system in suppressing monocyte production of tumor necrosis...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Sward, Eli W, Fones, Elizabeth M, Spaan, Russel R, Pallister, Kyler B, Haller, Brandon L, Guerra, Fermin E, Zurek, Oliwia W, Nygaard, Tyler K, Voyich, Jovanka M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191620/
https://ncbi.nlm.nih.gov/pubmed/29272502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix652
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